Dr. Ivo Sah Bandar successfully publishes new study on HIV Drug Resistance – June 2017
AIDS Res Hum Retroviruses. 2017 Jun 1. doi: 10.1089/AID.2016.0151. [Epub ahead of print] Ultra-Deep Sequencing Analysis on HIV Drug-Resistant-Associated Mutations among HIV-Infected Individuals: First Report from the Philippines.
HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/- (RAG1-Hu) and BLT Mice
Ginwala R et al J Neuroimmune Pharmacol. (2017)
Role of Natural Killer Cells in HIV-Associated Malignancies
Leal FE, et al. Front Immunol. 2017
Plasminogen Activator Inhibitor-1 Predicts Negative Alterations in Whole-Body Insulin Sensitivity in Chronic HIV Infection
Wirunsawanya K, et al. AIDS Res Hum Retroviruses. 2017
High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy
Gangcuangco LM, et al. Medicine (Baltimore). 2016
Frailty Characteristics in Chronic HIV Patients are Markers of White Matter Atrophy Independently of Age and Depressive Symptoms: A Pilot Study
Kallianpur KJ, et al. Open Med J. 2016
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment
Corley MJ, et al. Sci Rep. 2016
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation
Abdel-Mohsen M, et al. PLoS Pathog. 2016
Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy
Chow DC, et al. HIV Clin Trials. 2016
Elevation of Non-Classical (CD14+/lowCD16++) Monocytes Is Associated with Increased Albuminuria and Urine TGF-β1 in HIV-Infected Individuals on Stable Antiretroviral Therapy
Mitchell BI, et al. PLoS One. 2016
Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients
Kallianpur KJ, et al. Mitochondrion. 2016
Strategies to target non-T-cell HIV reservoirs. Sacha JB, Ndhlovu LC. Curr Opin HIV AIDS. 2016 Jul;11(4):376-382.
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK.PLoS Pathog. 2016 Jun 2;12(6):e1005677. doi: 10.1371/journal.ppat.1005677. eCollection 2016 Jun.
CD4/CD8 Ratio Predicts Peripheral Fat in HIV-Infected Population. Riangwiwat T, Kohorn LB, Chow DC, Souza SA, Ndhlovu LC, Wong JW, Gangcuangco LM, Shikuma CM. J Acquir Immune Defic Syndr. 2016 May 1;72(1):e17-9. doi: 10.1097/QAI.0000000000000955. No abstract available.
Elevation of Non-Classical (CD14+/lowCD16++) Monocytes Is Associated with Increased Albuminuria and Urine TGF-β1 in HIV-Infected Individuals on Stable Antiretroviral Therapy. Mitchell BI, Byron MM, Ng RC, Chow DC, Ndhlovu LC, Shikuma CM. PLoS One. 2016 Apr 20;11(4):e0153758. doi: 10.1371/journal.pone.0153758. eCollection 2016.
Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM.HIV Clin Trials. 2016 May;17(3):114-22. doi: 10.1080/15284336.2016.1162386. Epub 2016 Apr 4.
Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients. Kallianpur KJ, Gerschenson M, Mitchell BI, LiButti DE, Umaki TM, Ndhlovu LC, Nakamoto BK, Chow DC, Shikuma CM. Mitochondrion. 2016 May;28:8-15. doi: 10.1016/j.mito.2016.02.006. Epub 2016 Feb 23.
Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy. Zungsontiporn N, Tello RR, Zhang G, Mitchell BI, Budoff M, Kallianpur KJ, Nakamoto BK, Keating SM, Norris PJ, Ndhlovu LC, Souza SA, Shikuma CM, Chow DC. PLoS One. 2016 Feb 11;11(2):e0149143. doi: 10.1371/journal.pone.0149143. eCollection 2016.
Atazanavir use and carotid intima media thickness progression in HIV: potential influence of bilirubin. Chow D, Kohorn L, Souza S, Ndhlovu L, Ando A, Kallianpur KJ, Byron MM, Baumer Y, Keating S, Shikuma C. AIDS. 2016 Feb 20;30(4):672-4. doi: 10.1097/QAD.0000000000000970.
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection published in the January 2016 issue of the scientific journal PLoS Pathogens.
Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy. Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC. HIV Clin Trials. 2015 Nov;16(6):228-35. doi: 10.1080/15284336.2015.1123943.
The meningeal lymphatic system: a route for HIV brain migration? Lamers SL, Rose R, Ndhlovu LC, Nolan DJ, Salemi M, Maidji E, Stoddart CA, McGrath MS. J Neurovirol. 2015 Nov 16.
Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy. Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC. HIV Clin Trials. 2015 Nov;16(6):228-235.
Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais. Ndhlovu LC, D’Antoni ML, Ananworanich J, Byron MM, Chalermchai T, Sithinamsuwan P, Tipsuk S, Ho E, Slike BM, Schuetz A, Zhang G, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Valcour V. J Neuroimmunol. 2015 Nov 15;288:25-33. doi: 10.1016/j.jneuroim.2015.08.020. Epub 2015 Sep 4.
Preclinical development of HIvax: Human survivin highly immunogenic vaccines.Hoffmann PR, Panigada M, Soprana E, Terry F, Bandar IS, Napolitano A, Rose AH, Hoffmann FW, Ndhlovu LC, Belcaid M, Moise L, De Groot AS, Carbone M, Gaudino G, Matsui T, Siccardi A, Bertino P.Hum Vaccin Immunother. 2015;11(7):1585-95. doi: 10.1080/21645515.2015.1050572.
Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA.J Virol. 2015 Apr;89(7):3723-36. doi: 10.1128/JVI.00006-15. Epub 2015 Jan 21.
Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN.AIDS Res Hum Retroviruses. 2015 Feb;31(2):221-8. doi: 10.1089/AID.2014.0239. Epub 2014 Dec 29.
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques. Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, Ishii N, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC. J Immunol. 2014 Dec 1;193(11):5576-83. doi: 10.4049/jimmunol.1400961. Epub 2014 Oct 27.
Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associated neurocognitive disease (HAND). Ndhlovu LC, Umaki T, Chew GM, Chow DC, Agsalda M, Kallianpur KJ, Paul R, Zhang G, Ho E, Hanks N, Nakamoto B, Shiramizu BT, Shikuma CM.J Neurovirol. 2014 Dec;20(6):571-82. doi: 10.1007/s13365-014-0279-x. Epub 2014 Sep 17.
Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy.O-charoen P, Ndhlovu LC, Gangcuangco LM, Keating SM, Norris PJ, Ng RC, Mitchell BI, Shikuma CM, Chow DC.AIDS Res Hum Retroviruses. 2014 Dec;30(12):1185-91. doi: 10.1089/AID.2014.0072.
Elevated levels of full-length and thrombin-cleaved osteopontin during acute dengue virus infection are associated with coagulation abnormalities.Chagan-Yasutan H, Lacuesta TL, Ndhlovu LC, Oguma S, Leano PS, Telan EF, Kubo T, Morita K, Uede T, Dimaano EM, Hattori T.Thromb Res. 2014 Aug;134(2):449-54. doi: 10.1016/j.thromres.2014.05.003. Epub 2014 May 14.